Same, but with a hybrid and a minivan. We use the hybrid whenever possible (~2x the gas efficiency, cheaper repairs, etc). It's not a big deal, and our adjusting process is completely manual (adjust seatbelt, seat, and mirrors) since we're very different heights.

I haven't done the math, but I imagine it saves hundreds every year on gas alone. We put something like 15k miles on the small car, and 5-10k miles on the big car.