669
There can be only one winner
(lemmy.world)
you are viewing a single comment's thread
view the rest of the comments
view the rest of the comments
this post was submitted on 19 Sep 2024
669 points (98.5% liked)
Memes
8407 readers
992 users here now
Post memes here.
A meme is an idea, behavior, or style that spreads by means of imitation from person to person within a culture and often carries symbolic meaning representing a particular phenomenon or theme.
An Internet meme or meme, is a cultural item that is spread via the Internet, often through social media platforms. The name is by the concept of memes proposed by Richard Dawkins in 1972. Internet memes can take various forms, such as images, videos, GIFs, and various other viral sensations.
- Wait at least 2 months before reposting
- No explicitly political content (about political figures, political events, elections and so on), !politicalmemes@lemmy.ca can be better place for that
- Use NSFW marking accordingly
Laittakaa meemejä tänne.
- Odota ainakin 2 kuukautta ennen meemin postaamista uudelleen
- Ei selkeän poliittista sisältöä (poliitikoista, poliittisista tapahtumista, vaaleista jne) parempi paikka esim. !politicalmemes@lemmy.ca
- Merkitse K18-sisältö tarpeen mukaan
founded 2 years ago
MODERATORS
So caffeine binds to adenosine receptors to block adenosine's drowsiness effect. Melatonin binds to melatonin receptors to regulate circadian rhythms. As far as how adenosine interacts with melatonin, no idea. I'm no biochemist and what I'm about to say could be 100% incorrect, but it seems that adenosine is involved in melatonin production?
So if it's true that adenosine leads to melatonin production, then I'm guessing that the adenosine-blocking effect of caffeine would be (partially?) negated by ingesting a melatonin supplement, especially in the massive doses that they sell.
~~My money is on SLEEP.~~ [I got it backwards!! See below replies.]
You’re on the right track, but funnily enough you got it switched around!
Research shows that melatonin binding leads to downstream release of adenosine, so if caffeine is blocking its binding action sleep is not on the way!
Here’s the paper I am referencing: https://doi.org/10.1016%2Fj.neuron.2015.02.016
“We find that melatonin promotes sleep downstream of the circadian clock as it is not required to initiate or maintain circadian rhythms. Additionally, we provide evidence that melatonin may induce sleep in part by promoting adenosine signaling, thus potentially linking circadian and homeostatic control of sleep”
Ohh so melatonin leads to adenosine production, which caffeine blocks. so NO SLEEP is the smart bet. that makes a lot of sense, yeah! and when you think about it, coffee at night is gonna make for poor sleep no matter how much melatonin you take.