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Other 196's:
Unfamiliar with this particular discourse. Are they opposed to it because it's illegal? Or are they worried that it's dangerous because even most of us who did well in chemistry and biology in high school probably wouldn't feel comfortable doing it ourselves or trusting unregulated strangers?
My initial concern is that HRT is a powerful substance requiring close monitoring by a doctor. Too much or too little can wreak havoc on your body. It's a delicate balance. Now if you're able to convince a doctor to monitor your levels and tell you if your dosage is correct, then I see no issue.