I haven't tried any Anthropic models personally.
So far, between the free online chats by OpenAI and DeepSeek, and the smaller models I've run on my own machine, the most useful things I have gotten from it were to treat it as an overeager student that lacks the first-hand experience needed to see the big picture, asking it questions that I'm pretty sure I already know the answer to and seeing if 1) it "understands" what I'm getting at and 2) it can surprise me with a viewpoint I hadn't thought of before.
Using them to double-check my own ideas seems to be marginally useful, especially when there's no qualified human being whose attention I can borrow. Using them as a sort of semantic web search can sometimes get me what I'm looking for faster than Google. If anything, they're an opportunity to exercise critical thinking; if I can tell where it's getting things wrong I can be fairly confident that my own understanding of the problem/subject is pretty solid.
Vibe coding, though? I have yet to see it work out. Maybe as some starting slop so that I can get to work refactoring code (and get the ideas flowing) instead of staring at a blank file.