Theoretically if you rotated the creature 180°, it could again perceive things from its own world, though in a very different way. But you'd think a sufficiently smart 2 dimensional creature could come to recognize that it was indeed the same world just mirrored.

Though it's possible this creature's chemistry would have a "handedness" and it could no longer metabolize the nutrients that exist in that world.

This isn't really a book about being 2d, rather creatures being flattened by a stars gravity thar they live in.

It's called Dragon's Egg And was a really tripped read.

The plot is essentially a group of scientists go study a neutron star with some advanced tech (related to what we have now) that helps them weather some gravity problems. They discover that the star is inhabited by creatures made from nuclei bound by the strong force. They try to communicate with these tiny sesame sized creatures, but 1 of their days = 0.2 seconds human time... so communication is tricky.

https://youtu.be/avMX-Zft7K4 only watched the movie

Not sure about "great" but it's definitely a book. lol

That reminds me of the Action Lab video on a 4D ball.

https://youtu.be/_4ruHJFsb4g

You might like this video on a 4d physics engine

Lovecraft wrote more about how finding out about new, unknowable information and understanding (or attempting to understand) can drive someone insane. So similar, but without the physical aspect (although tbf he also used physical transformation as an idea too, like people turning into fish monsters).