Here you go: KLGA/04 N0452F380 DCT GAYEL Q818 WOZEE LINNG3 CYYZ/15L
And OP is wrong, the flight is too short to use great circles (376nm gnd dist).
But if you like nice routes, this is a (not flown) polar route between Tokyo and Paris
Not flown because of the Russian Airspace ban so few airlines fly them (I think only Emirates, Qatar and JAL can still fly them).
Others do the long "FIR avoidance route" like this Paris Hong-Kong
Edit: Hell, I found an old PHNL-LGAV that is totally not flown IRL but it creates a nice straight north line that is indeed a great circle around the pole (7300nm)
I think OP is talking about the anti HIV PrEP pill, which is a cool thing but hard to get.