Very different than, say, New Vegas where all the enemies that fill the "Raider" or "Bandit" niche are named factions with actual reasons for existing and histories that make sense. Legion, Vipers, Jackals, Khans, Fiends, Powder Gangers, and so on, and each of them has their own aesthetic and gameplay touches.

Well sure, I guess 90% of the enemies could just be random jet/psycho addicts wearing scrap metal who rush your power armored ass with a pool cue while yelling "Kickass!". That's fine too I guess...