There was an edgy but very fun indie game a few years ago (maybe 5-6?) where one player played as a parent running around and childproofing the house while the other played as the baby trying to kill themselves. The game was surprisingly fun, and weirdly putting the logic you'd heard your entire life to keep children safe to die was always quiet funny, from getting forks to plugs to filling the bath etc.

Taking inspiration to make a game in a psyche ward in a jail break / death is victory multiplayer game would probably make for a popular streaming game, although the topic is as horrible as the baby death game, perhaps worse because instead of being in the role of a silly unfortunate baby, you'd be in the role of somebody fully aware and acting with premeditation.