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submitted 10 months ago by fossilesque@mander.xyz to c/science@mander.xyz
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[-] HowRu68@lemmy.world 40 points 10 months ago

We should live in Shroom world, everybody will be connected by the mycelium, live long and prosper together.

[-] NaibofTabr@infosec.pub 20 points 10 months ago

Yes... let the cordyceps eat your brain... become one with the omnifungi... let our will become yours... listen to the mold as it whispers in your mind...

[-] Mac@mander.xyz 9 points 10 months ago

🤷‍♂️

Okay, sure, why not

[-] Vanilla_PuddinFudge@infosec.pub 3 points 10 months ago

Eh, beats fascism.

[-] lb_o@lemmy.world 2 points 10 months ago

WE ARE THE ONE!

[-] steal_your_face@lemmy.ml 2 points 10 months ago

I am the Globglogabgalab

[-] otter@lemmy.dbzer0.com 1 points 10 months ago

Did you drop this? /s

You're making it sound pretty damn amazing, frankly. Have you looked around lately? 😅😶‍🌫️

[-] Mac@mander.xyz 0 points 10 months ago* (last edited 10 months ago)

edit: double post

[-] redchert@lemmygrad.ml 1 points 10 months ago

There is already fungi that grows in your throat. Humans are connected to the mycelium - the most advanced lifeform on this planet.

[-] jeffw@lemmy.world 29 points 10 months ago

Forgive me for doubting any studies that don’t involve blinded trials… but this is just one study. Let’s see if it can be replicated before we get excited

[-] remotelove@lemmy.ca 14 points 10 months ago

Oh, I am going to try to replicate this study. I'll hit you back in about 50 years if it worked.

[-] jeffw@lemmy.world 2 points 10 months ago

It takes you 50 years to transform into a mouse?

[-] remotelove@lemmy.ca 1 points 10 months ago

Or sooner, once the medicine kicks in.

[-] jeffw@lemmy.world 1 points 10 months ago

Whoa. You’re a mouse now?

[-] BodyBySisyphus@hexbear.net 9 points 10 months ago

Results indicated that the mice that received an initial low dose of psilocybin of 5 mg/kg, followed by a monthly high dose of 15 mg/kg for 10 months, had a 30% increase in survival compared to mice who hadn’t received any.

So if we take a standard 80 kg adult male, 80 * 15 mg = 1.2 g, which sources indicate is enough for a standard trip. That's also like almost half an ounce of dried mushrooms. Time to start tripping... for science.

[-] HootinNHollerin@lemmy.dbzer0.com 5 points 10 months ago
[-] BodyBySisyphus@hexbear.net 8 points 10 months ago

Yeah, the paper is talking about pure Psilocybin. I double checked and the rule of thumb is around 1% psilocybin by dry weight so I was actually off and you'd need closer to three ounces.

[-] Castor_Troy@hexbear.net 4 points 10 months ago* (last edited 10 months ago)

(15 mg psilocybin / 1 kg body weight) * 80 kg body weight = 1200 mg psilocybin

1200 mg psilocybin * (1 g psilocybin / 100 g dried mushrooms) = 12 g dried mushrooms

I think it's 12 grams dried mushrooms, which is almost half an ounce, like you first said.

[-] Maturin@hexbear.net 7 points 10 months ago

Shouldn’t it be 1200 mg / 0.01 = 120 g of dried mushrooms?

[-] Castor_Troy@hexbear.net 2 points 10 months ago

Thank you. I was staring at it and knew the units weren't canceling out. That's an insane dose though.

[-] Maturin@hexbear.net 4 points 10 months ago

Even the “low dose” is the equivalent of almost 2 oz per dose. Those mice got to convene with the mice gods on the reg I’m sure.

[-] propter_hog@hexbear.net 4 points 10 months ago

Boofing a whole tray of penis envy shrooms... for science

[-] Castor_Troy@hexbear.net 2 points 10 months ago

(15 mg psilocybin / 1 kg body weight) * 80 kg body weight = 1200 mg psilocybin

1200 mg psilocybin = 1.2 g psilocybin * (100 g dried mushrooms / 1 g psilocybin) = 120 g dried mushrooms

There we go.

[-] Laser@feddit.org 9 points 10 months ago

A newly published study in Nature Partner Journals’ Aging demonstrates that psilocin, a byproduct of consuming psilocybin, the active ingredient in psychedelic mushrooms,

Maybe my memory is wrong, but I had it the other way around: Psilocin is the active substance, but its not very stable. Psilocybin gets metabolized to Psilocin. Calling it a "byproduct" is kind of underselling it. Psilocybin itself isn't active by itself.

Quick wiki check confirms this. I always have troubles with articles opening with. I can't even read that as unfortunate wording.

[-] sixtoe@lemmy.blahaj.zone 8 points 10 months ago

HOLY SHIT IM GONNA LIVE FOREVER

[-] wideopenarms@hexbear.net 3 points 10 months ago* (last edited 10 months ago)

Idc, I'll just die old, no one's ever gonna get me to willingly take hallucinogens

Go ahead and hit me with the downbear, don't care if that's an L take or not

[-] otter@lemmy.dbzer0.com 2 points 10 months ago

You do you. Have fun!

[-] isolatedscotch@discuss.tchncs.de 0 points 10 months ago

no healthy adult should feel the need to take any drug

[-] Rivalarrival@lemmy.today 0 points 10 months ago

Need? Of course not. Desire? Certainly.

[-] ogmios@sh.itjust.works 3 points 10 months ago

Well, I know I've done mushrooms a few times, and as of a CT scan at the age of 27, apparently my brain isn't showing the ordinary signs of aging. Wonder if it's related.

[-] BurgerBaron@piefed.social 16 points 10 months ago

You'd have to microdose regularly for it to matter if it actually does anything in humans for our telomeres.

[-] ogmios@sh.itjust.works 0 points 10 months ago

Wow you sure seem to know one hell of a lot about the inner workings of this newly discovered phenomena.

[-] BurgerBaron@piefed.social 6 points 10 months ago

Your sarcasm is noted, but seems daft when you suggest you'll live longer because you ate a funny mushroom a couple times.

[-] ogmios@sh.itjust.works -1 points 10 months ago

Not sure where you read any of that in my posts.

[-] Hirom@beehaw.org 1 points 10 months ago

Wake me up when once there are results of a well-designed clinical trial.

My understanding of the article is they're extrapolating from experiments on mice and on a few human cells in a lab.

[-] Bronzebeard@lemmy.zip 1 points 10 months ago

Nuh uh. I've seen the Last of US. We all know where this ends up

this post was submitted on 24 Jul 2025
152 points (98.7% liked)

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