It depends a lot on the game. I've played a lot of switch games with no problems on my 12600k and 6800xt. The new Zelda game was really hard to play, though, even with all of the various performance tweaks and mods available 3 months after the launch. Frame rate drops, glitches, timing flaws, bugs, etc. It's probably in a better state now, but I got sick of trying the latest settings and mods and still having issues.

I have a similar setup to yours, and can offer my experience:

Got a regular clocked ryzen 7 3700x and a radeon rx 5700. I use ryujinx, but only played TotK on it.

my pc just laughed at the 60fps mod but got 30fps at 720p resolution nearly always above ground, and usually in the depths though the depths especially had intermittent times where i was chugging along at only 10fps. I think it was something to do with the cache, but i never isolated the cause.

I would say you'll probably have slowdowns but will generally perform better than my rig which is acceptable if not great for switch emulation

EDIT: other specs that might affect performance:

• 64G ram

• Crucial M.2 hdd

• VERY pretty LEDs

If it can emulate PS4, it'll handle Switch like a breeze. Your specs are overkill for that level. Switch runs on what is effectively potato hardware compared to most new entry level PCs and it's a couple generations behind consoles.

That said, I unironicly think it's the best system ever built.

Using Ryujinx I think you should be more than fine with those specs relative to the Xenia experience (but if for some reason they're not please let me know)