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submitted 3 weeks ago* (last edited 3 weeks ago) by Buttflapper@lemmy.world to c/mildlyinfuriating@lemmy.world

I don't see how this is legal, but people on Tik Tok peddling miracle "medicine" are becoming more common every day. No FDA approval, no research. Just their marketing hype and false promises. This one, lady is showing some sort of probiotic and claiming it can help people suffering from severe acid reflux and gastrointestinal reflux disease or GERD, replacing medicine that has been tested for decades.

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[-] protist@mander.xyz 183 points 3 weeks ago

This was all made legal in the Dietary Supplement and Health Education Act of 1994.

Before that, everythimg required FDA approval, but now if it says "natural" or "not intended to treat any condition" on the side, you can bottle and sell your own piss if you've got a good enough sales pitch

[-] quixotic120@lemmy.world 64 points 3 weeks ago

The important takeaway from this is that “supplements” have 0 oversight. The CBD, probiotics, vitamin d, etc that you buy could just be capsules of vegetable oil that does nothing at all. Or they could be asbestos and cyanide for all you know (that probably would lead to an investigation though). There’s also no safety regarding packing and handling, so it might literally be a guy with unwashed hands who just picked his butt loading your gelcaps in a dirty bathroom that someone just took a massive shit in. No one checks and verifies any of this and that’s why shills and hucksters jump onto this shit, it’s a completely unregulated market where can cut corners everywhere and say whatever you want as long as you include *not intended to treat any diseases and not evaluated by the fda

A $1200 thing you buy on instagram that sends “good waves” to your brain? Supplement. The cbd you buy at the gas station? Supplement. Doterra oils? Supplement. No regulation, no oversight, just robbing people based on their desperation to fix chronic pain and mental illness

[-] SnotFlickerman@lemmy.blahaj.zone 43 points 3 weeks ago* (last edited 3 weeks ago)

So the CBD thing really bugs me, in particular.

One of my medications has one of those warnings about how you can't have grapefruit while taking this medication. That's because grapefruit is metabolized on a certain enzyme pathway that gets interrupted. That enzyme pathway is CYP3A4.

You know what else takes that enzyme pathway? Fucking CBD. It also blocks the enzyme pathway, making any drugs administered less effective because they can't bind to where they need to because the CBD molecule is already there, taking up space.

So like, for me, these are life saving medications so fucking around with this is really stupid but literally no doctor told me this. I accidentally figured this out while doing research on CBD. It seems like its becoming more publicized now, but the bottom line is this:

If you have medication that warns you that you should not eat grapefruit with this medication (about 60% of medications, I believe), that medication needs the same warning about CBD.

https://www.pharmacytimes.com/view/cannabidiol-presents-conundrums

Upon further evaluation, it was shown that CYP3A4 and CYP2C19 are the 2 major enzymes responsible for the metabolism of CBD; they are also responsible for the metabolism of many different drugs.

[-] deranger@sh.itjust.works 9 points 3 weeks ago* (last edited 3 weeks ago)

It only makes prodrugs that first need to be metabolized by CYP3A4 to be active less effective. This is a pretty small minority of drugs. It makes drugs that are inactivated by CYP3A4 more effective, which is the majority of them. It also only competitively inhibits the enzyme while the drug is in your system, it’s not permanently inhibiting the enzyme like a suicide inhibitor.

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[-] remotelove@lemmy.ca 17 points 3 weeks ago

You can actually find small bottles of water on Amazon marketed as a miracle cure.

[-] thurstylark@lemm.ee 26 points 3 weeks ago
[-] remotelove@lemmy.ca 16 points 3 weeks ago* (last edited 3 weeks ago)

Just stay away from nearly anything that uses "healing ions" in its marketing material. If it's not a straight-up fake product, it'll likely kill you in due time. (Ozone generators are an exception unless you get a beefy one like mine, and then it can actually kill you.)

Edit: lol! I have seen that video and made my comment about ions before I clicked it. Good video, btw. 5 stars.

[-] JusticeForPorygon@lemmy.world 8 points 3 weeks ago

What I don't get about these products, is the use of radioactive material intentional? Do the people making this shit do it with the intention of giving people rings covered in thorium? If not, then why does it happen? Is the manufacturing process just so sketchy that it somehow gets cross contamination with actual fucking nuclear reactor fuel?

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[-] nobleshift@lemmy.world 14 points 3 weeks ago

William Murderface has entered the chat

[-] CulturedLout@lemmy.ca 5 points 3 weeks ago

Wow. You'd think "natural" would be more heavily regulated since a lot of people consider it to be a synonym for "harmless" (I am not one of them)

[-] MelodiousFunk@slrpnk.net 89 points 3 weeks ago

That probiotic is nice and all, but it'll never beat apple cider vinegar. That stuff cures everything. Especially if you take it with silver.

Seriously though, this is just the latest venue for this kind of bullshit.

[-] HeyThisIsntTheYMCA@lemmy.world 31 points 3 weeks ago

Excuse me putting an onion in my grandfather's sock overnight cured him of death twice

[-] MelodiousFunk@slrpnk.net 10 points 3 weeks ago

I hope you don't take the onion from his belt.

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[-] sp3tr4l@lemmy.zip 19 points 3 weeks ago

Personally I'm a fan of Smurf Juice brand colloidial silver.

[-] SerJunkan@lemmy.world 14 points 3 weeks ago

Should I take this with my nightly mercury eye drops?

[-] clif@lemmy.world 7 points 3 weeks ago

You're supposed to put a link to where we can buy your miracle vinegar/silver mix in your post. Have you learned nothing from these marketing geniuses?

[-] MelodiousFunk@slrpnk.net 8 points 3 weeks ago

My bad.

https://127.0.0.1/C$/%userprofile%/Documents/EXCEL.ppt

If that doesn't work give Derek a call.

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[-] Zier@fedia.io 73 points 3 weeks ago
[-] psmgx@lemmy.world 13 points 3 weeks ago

Ehh more like marketing. But clearly pushing snakeoil in this case.

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[-] AFC1886VCC@reddthat.com 63 points 3 weeks ago

We're getting dangerously close to social media apps where you scroll through ads and only ads. Maybe we're already there..

[-] irotsoma@lemmy.world 16 points 3 weeks ago

My Facebook and Instagram are now >3/4 stuff that I didn't follow. Not all are explicitly advertisements, but they aren't things I wanted to see. That's why I'm moving to federated services. Just wish I could convince more of my friends and family to move over. I use Lemmy as a replacement for Reddit so it's more widely social, but the other stuff I only really used for friends, family, or special interest groups.

[-] Thebeardedsinglemalt@lemmy.world 6 points 3 weeks ago

Man am I glad I killed my FB back In 2012 when it was mostly pictures of peoples babies and people acting like hating Obama was a personality trait

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[-] TheTechnician27@lemmy.world 49 points 3 weeks ago

Congress needs to give the FDA the power to regulate supplements goddamn yesterday.

[-] JusticeForPorygon@lemmy.world 33 points 3 weeks ago

They had it and it was taken away in the 90s

[-] AmidFuror@fedia.io 12 points 3 weeks ago
[-] roscoe@lemmy.dbzer0.com 7 points 3 weeks ago

And Mel Gibson. When they were lobbying to get rid of the regulations, the supplement industry did commercials that had Mel's home getting raided by SWAT-looking guys for having supplements.

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[-] Fester@lemm.ee 20 points 3 weeks ago

Best we can do is ignore everything while random judges give themselves power to override the FDA whenever it causes inconvenience to corporations.

— Congress

[-] remotelove@lemmy.ca 18 points 3 weeks ago

Yeah. The peddlers of homeopathic crap are the first ones that need to burn.

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[-] SnotFlickerman@lemmy.blahaj.zone 28 points 3 weeks ago* (last edited 3 weeks ago)

For some folks, like myself, it was admitting to myself that I needed to change my diet and eating habits, and I haven't had issues with acid reflux for years.

On the other hand, lots of folks have issues with this stuff no matter their eating habits and it is horrific to live with. As OP pointed out, things like GERD affect a lot of people.

That these people would take advantage of people in that situation is so infuriating.

[-] idiomaddict@lemmy.world 12 points 3 weeks ago

My ex was not noticeably sad about it, but I felt awful for him because of his GERD. He had to stop eating for the day at around 17:00, he couldn’t have caffeine, alcohol, carbonation, anything acidic, capsaicin, or much fat. His mother was from southern Italy and he hadn’t eaten a tomato in more than a decade, and the only fruit he ate was bananas. He was not big on medication, though, so he considered all that to be a good trade off for not taking meds. I can’t imagine making the same choice if a medicine could allow me to have oranges and tomatoes and coffee, but different strokes I guess

[-] remotelove@lemmy.ca 7 points 3 weeks ago

I was hoping that my heartburn would go away after I quit drinking a couple of years ago, but instead, it got worse. Honestly, that it's probably because I started to form an actual diet and my stomach didn't know what the fuck to do.

Sigh. I am hoping this current mega-cycle of proton-pump inhibitors helps. It's been a fairly high dose for about quadruple the normal length of time, so it might actually stick this time.

[-] SnotFlickerman@lemmy.blahaj.zone 6 points 3 weeks ago* (last edited 3 weeks ago)

Here's hoping they stick this time. I'm so sorry to hear, long ago one of my now ex-girlfriends was dealing with it. She would have to go to the hospital and get GI cocktails and I would stay awake with her and try to help her not panic because the GI cocktail numbed everything in your throat and she wouldn't be able to feel herself breathing. As someone who has lots of panic about breathing issues, I totally understood why it would be panic inducing to not be able to feel yourself breathe, and this seemed like the only thing anyone was able to do for her when it got really bad. Just a shitty choice, take the GI cocktail and get relief but also panic, or don't take it and feel like you're choking on your own vomit. So , fuck it just sucks so much. I really hope for the best for you.

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[-] alcoholicorn@lemmy.ml 5 points 3 weeks ago

The irritation caused by heartburn increases heartburn. So during your proton-pump inhibitor cycle, you still get heartburn, treat it with baking soda dissolved in warm for instant relief

[-] remotelove@lemmy.ca 7 points 3 weeks ago

For anyone else reading, baking soda can save you hundreds of dollars on regular antacids. One you get past the taste and train your body it brings relief, it'll be tasting like champagne soon enough.

LPT: Baking soda and water can burn your mouth and lips after a time as well, so keep it fairly dilute. More is sometimes needed, but not always better.

Second LPT: Get a second small box of baking soda for heartburn use and keep it sealed in a Ziploc or something. It will absorb all kinds of stuff out of the air and end up tasting really bad. (Name-brand baking sodas tend to taste a little less fishy as well, but not by much.)

Sorry, I know more about baking soda now than I care to admit. It's really a super interesting chemical, even in its simplicity.

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[-] sp3tr4l@lemmy.zip 26 points 3 weeks ago

I used to know sooo many people that would justify this, a cryptoscam, shilling literally any outright fraud or vastly overpriced bs on their social media.

'They're just getting their bag, you're hating cuz you broke!'

This is the cyberpunk dystopia.

[-] SnotFlickerman@lemmy.blahaj.zone 31 points 3 weeks ago* (last edited 3 weeks ago)

God damn took me forever to find one without that text file in it

[-] Cenotaph@mander.xyz 8 points 3 weeks ago
[-] SnotFlickerman@lemmy.blahaj.zone 9 points 3 weeks ago* (last edited 3 weeks ago)

Like this one:

Text file slightly laid over the n in the word cyberpunk.

The original high quality copy without this seems long deleted from reddit.

To find the one I did, I had to turn to tineye.

[-] Cenotaph@mander.xyz 8 points 3 weeks ago

Your hard work is appreciated, soldier. o7

[-] ValorieAF@lemmy.world 5 points 3 weeks ago

What the fuck lol

[-] HootinNHollerin@lemmy.world 13 points 3 weeks ago
[-] nokturne213@sopuli.xyz 13 points 3 weeks ago

Because i want to use TikTok.

[-] uienia@lemmy.world 5 points 3 weeks ago

Cool. Then you get what you want, because this is exactly what tiktok is.

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[-] bigkahuna1986@lemmy.ml 13 points 3 weeks ago

Side note, for me, steamed kale is doing wonders.

[-] remotelove@lemmy.ca 13 points 3 weeks ago

Kale has a naturally high pH, so it's basically just an antacid. If it works consistently for you, keep it up. No point in taking industrial strength meds for something simple, after all.

The class of drugs for my kind of heartburn are proton-pump inhibitors and help limit acid production across the board. It's good these are over the counter now as I am on a 2x dose, but have been as high as 4x before.

I switched from standard antacids to just water and baking soda my stomach was so bad. Kale wouldn't have put a dent in my stomach acid, TBH. I drink a ton of water these days, and even if the pH of the water was off by a hair, it would be a bad time.

I probably might be able to cut my dosage back or even stop soon hopefully. It's one of the few drugs that are actually supposed to provide a long term solution.

[-] partial_accumen@lemmy.world 5 points 3 weeks ago

Kale has a naturally high pH, so it’s basically just an antacid.

I have mild reflux, but know what triggers it after what time of day and can make easy diet adjustments to avoid those triggers too late before bed. For whatever reason, I never considered looking at the alkaline level of the foods I eat. In just doing so now, I see a whole bunch of my regular diet. Have I been unconscious choosing these to mitigate my reflux? I mean, I seek out these foods (that I now know are alkaline) because I like them, but do I like them more than just for their taste?

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[-] itsathursday@lemmy.world 5 points 3 weeks ago

Obviously and issue but on par with actual product advertising on TV that has 0 approval and more often that not lists death as a side effect.

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this post was submitted on 09 Sep 2024
309 points (95.6% liked)

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